Suzan Carson and her husband Michael - both of whom are mentally ill and abuse drugs - have a list of people they think are witches that they wish to exterminate, and they go on to viciously murder three people. 14-year-old Chelsea O'Mahoney becomes involved in a gang where she and three friends attack eight people in one night while videotaping the encounters; one man dies at their hands. Two men named Bob give Pamela Perillo and her boyfriend James Briddle a place to live and money in exchange for helping around their apartment. Sadly, they make a big mistake as one morning Pamela and James rob their hosts, strangle one Bob to death, eat the coffee and donuts that he had brought for them, and finally suffocate the other Bob
Missing her mother's companionship, beautiful and intelligent high school student Marie Robards poisons her loving father to move back in with her mom. She keeps it a secret for a year until her college roommate recites Claudius's guilt monologue from Hamlet, causing her to break down. The ways of wild, promiscuous "jazz baby" Dorothy Ellingson don't mesh with those of her old-fashioned parents who try to keep her from partying. Enraged at her parents and desperate for freedom, Dorothy shoots her mother in the head and goes partying afterwards. In prison, she appears to change her ways and begins to give lectures to teenagers on the dangers of delinquency.Brigitte Harris visits her sister and is surprised to see that also visiting is their child molester father who had been living in Liberia for several years. After he announces that he plans to return to Africa with his granddaughter; Brigitte handcuffs, suffocates and castrates her father to save her niece from a dreadful fate.
After Dena Thompson attempts to murder her new third husband with the lure of kinky sex, he barely survives and she gets three years in jail. Police eventually discover she's a gold-digger and murderer after finding large amounts of poison in the exhumed body of her second husband. Turn of the century Chicago wife/necrophile Louise Vermilyea uses arsenic to murder two husbands, five stepchildren and two other men for years before getting caught. She manages to escape prison by using the poison to harm herself and spends the rest of her days paralyzed. Brookey Lee West was raised with her father teaching her Satanism, witchcraft and violence, while her mother engages in numerous affairs and neglects her and her brother. As an adult, the hatred planted in Brookey's childhood leads her to gag her now needy, elderly mother with a grocery bag, stuff her into a trash can and put it into storage where it remains undisturbed for three years.
Frances Creighton resorts to poisoning her relatives with arsenic when they no longer become of use to her. After being acquitted of murdering her own brother, Frances moves to New York and begins an affair with a married man. Her lover's wife is a gossip who threatens to tell the neighbors about Frances' dark past, and Frances decides to silence her permanently. Betty Neumar had five husbands - four of whom died suspiciously while married to Betty. For decades, no one connects any of the deaths until a cold case investigation reveals Betty's murderous deeds. 72-year-old Millicent Cumberbatch and her husband Stanley were married for 38 years, but their union wasn't always a happy one. After a formal separation and her husband's year-long affair, a scorned and heartbroken Millicent decides to end their marriage, permanently.
Elisa Baker has her online lover/husband and his young daughter move from Australia to North Carolina to be with her. Elisa takes delight in torturing her stepdaughter Zahra, who earlier survived bone cancer that left her almost deaf and took one of her legs. Zahra eventually dies and Elisa dismembers her body. Della Sutorius comes off as a sweet, charming and beautiful woman to the men who fall in love with her, but her true colors come out after the weddings. She turns out to be a greedy, violent monster whose five husbands end up either on-the-run, abused, or (in the last husband's case) murdered for money. Sandy Cain ditches her life in New York to be with a bounty hunter husband named Frank in Las Vegas, whom she meets over the Internet. However, after they marry, Frank is revealed to be manipulator who gave Sandy nothing she had been hoping for. Feeling fed up due to his betrayal, she shoots him and tries to save herself by trying to make it look like a self-defense attempt gone wrong.
Theresa Riggi's lack of trust in others leads her to isolate her children from society and have complete control over them. Furious at this, her husband gets four-hour visitations every week upon divorcing her and when he tries to apply for full custody, she stabs all three children and makes an unsuccessful attempt to commit suicide. Elise Ledvina is known in Milwaukee as a caring Catholic mother who values setting a good example, but secretly battles with intense delusions due to schizophrenia. Convinced she's a bad mother and that this world was a bad place for her two sons, the voices in her head drive her to bludgeon them with a baseball bat; her elder son is saved due to his father's intervention, but the younger son dies. She is acquitted by reason of insanity. Young Philadelphia housewife Marie Noe never really wanted children, unlike her devoted husband Arthur, and is unable to emotionally cope with the stresses of motherhood. Over two decades, she gives birth to ten children and two of them are stillborn, but none of the surviving children live long as she smothers them when they're alone. She isn't caught until 50 years after the first murder.
Egyptian-born nanny and model Omaima Nelson has a track record of manipulating men; as a young woman, she begins seducing older men, then robbing them blind. In 1991, 23 year-old Omaima meets 56 year-old Bill Nelson. Instead of simply robbing her new husband, she murders him, and doesn't stop there. She goes on to dismember and consume his corpse. Lyda Trueblood is an early twentieth-century woman with a penchant for poison. She uses arsenic to kill several relatives, including her husbands and her own daughter. After getting caught for the crimes, Lyda escapes, and almost commits another poison murder before getting caught. Amy DeChant is a businesswoman who falls for Las Vegas bookie Bruce Weinstein. Shortly into their relationship, Bruce uses his monies to spoil Amy, who gets accustomed to living the good life, but when Bruce threatens to leave the relationship, Amy kills him and robs him of over $100,000.
In 1983, Jacksonville, Florida woman Andrea Hicks Jackson calls police to file a report about a vandalized car, but when officer Gary Bevel arrives on the scene, he learns that Andrea has committed the vandalism herself in a fit of rage. While Bevel attempts to arrest Andrea for filing a false report, Andrea shoots the officer five times. She is sentenced to death, but her sentence is later commuted to life in prison. Alyssa Bustamante, who was constantly neglected by her drug-addict mother, grows into a gothic teen with dark fantasies. In 2009, the 15 year-old lures 9 year-old Elizabeth Olten into the woods, where she uses a knife to slash the 9-year-old's throat, and uses her bare hands to strangle Elizabeth to death. Afterwards, Alyssa disposes of Elizabeth's body in a pre-dug grave. 17-year-old Felicia Morgan is an inner-city Milwaukee teenager on the fast track to a life of crime. In October 1991, Felicia encounters Brenda Evans and demands Brenda's leather coat. Brenda fights back, so Felicia shoots her to death and then wears Brenda's bloody coat.
Natasha Cornett is an outcast in her rural Kentucky town due to her Gothic appearance and devil worship. However, she soon finds like-minded friends, who decide to embark on a killing spree. In 1997, Natasha and her gang are responsible for the killings of a Jehovah's Witness family at a Tennessee rest area. Natasha and her gang each get life without parole. Brooklyn teen Tiana Browne appeared to have a promising start in life, until she was raped and ran away from home. Taken in by her aunt, Tiana becomes roommates with her cousin Shannon, who is a straight-A student, but Tiana resists their efforts to help her get on the right track. Tiana, jealous of her cousin's success, stabs Shannon to death, then steals Shannon's sneakers and cell phone. Australian teen Helen Moore is every parents' worst nightmare. In 1979, while working as a babysitter, she suffocates two infants in her care. Thereafter, she strangles her seven-year-old brother to death, and is turned in by her devastated mother. She receives a life sentence, but is paroled after only thirteen years.
Malaika Griffin is known as a brilliant chemist who graduated from college cum laude, but has a hot temper and harbors an intense hatred for white people. One night, she gets into a heated argument with her white neighbor, Jason Horsley, and his girlfriend. When the girlfriend leaves, Malaika shoots Jason in the back and flees while he dies, evading capture for several years. Ellen Etheridge is ecstatic when she gets to marry her new millionaire husband after his wife passes away. However, she's not so fond of having to fight for his love due to her eight new stepchildren and finds pleasure in poisoning them with lye to get her way. She ultimately kills four children and is suspected of killing her husband's first wife as well. Scottish restaurant chef Pamela Gourlay takes a dangerous mix of pills and pot with her boyfriend, but soon finds herself low on cash as a result. High as a kite, she fixes her problem by brutally stabbing her neighbor Melanie Sturton to death and stealing a few dollars and a gift card.
Heather Stephenson Snell is a well-educated psychotherapist by day, and a hard-laced biker gang leader by night. After a failed courtship with her lover, Heather wants revenge, and she sets her sights on her ex-lover's wife, Diane Lomax. Posing as a trick-or-treater on Halloween night, Heather attempts to shoot Diane with a shotgun, but winds up shooting a neighbor instead. In the 1890s, Anne Bradley becomes infatuated with married Utah Senator Arthur Brown. The two begin an affair, but Arthur is eventually forced to choose between Anne and his wife. When his wife dies, Arthur breaks up with Anne too. Anne responds by shooting Arthur to death. Brittany Norwood is a career thief, who lost her college scholarship by stealing from her teammates. Her thefts continue as she works for a Maryland clothing store. When Brittany's supervisor catches her shoplifting from the store, Brittany devises a brutal plan and commits a torturous murder.
Stacey Barker is at first a devoted single mother to 18-month-old Emma, but the novelty of motherhood wears off, and she spends her nights partying while her mother watches Emma. When Stacey's boyfriend tells her he does not want to be a father to Emma, she resorts to suffocating her daughter, then trying to disguise the murder as a kidnapping/rape. Kelly Silk is a born-again Christian and a mother of four children, including a 2 month-old baby. However, Kelly is a tortured soul, having witnessed her own mother's suicide as a child and continuing to suffer from extreme post-partum depression, which spirals out of control. Kelly goes on a rampage which results in the deaths of her husband, two of her children, and herself. At age 4, Nicole Diar survived being severely burned over most of her body. At 28, she has a 4-year-old of her own, Jacob; however, she is an unfit mother, leaving Jacob in the care of irresponsible teenage babysitters and drugging him with codeine to get him to sleep. In August 2003, Nicole drowns Jacob in the bathtub and sets their Ohio home on fire to cover the evidence. She is now serving a life sentence.
Child abuse victim Debra Brown is a mentally challenged young woman who has a "master/slave" relationship with her boyfriend, Alton Coleman. In 1984, the two embark on a killing spree through several Midwestern states. Coleman is sentenced to death, Brown to life in prison. Janice Buttrum was neglected, abused and ostracized by her peers as a child, and at age 17, she is married, living in Dalton, Georgia, and expecting her second child. She and her husband befriend Demetra Faye Parker, and one night they decide to use Demetra in a kinky sex game. Demetra is beaten and raped, and stabbed 97 times by Janice. Michelle Michaud, begins a turbulent relationship with James Daveggio, with whom she seeks greater sexual thrills, abducting and raping several young women, including her own daughter. In December 1997, they become murderers when they kidnap, rape, torture, and strangle 22-year-old Vanessa Lei Samson.
Manling Williams enjoys her freedom, finding life as a wife and mother too confining, but does not want the financial strain of divorce. Despondent after her extramarital affair ends, she turns to murder, smothering her two young sons with a pillow and slashing her husband, Neal, 97 times with his prized Japanese sword. In mid-20th century Alabama, Rhonda Belle Martin takes the lives of two husbands, three children, and her mother, and leaves a surviving husband paralyzed, via arsenic poisoning. Her motive is that she is addicted to killing and enjoys the thrill. Before her execution in 1957, she leaves her brain to science. Feeling lonely while her husband, Jim, works nights, Marilyn Plantz seeks solace in the arms of a lover more than half her age. At her urging, her boyfriend and his friend murder her husband by beating him to death and then burning his body to make it look like an accident, so that Marilyn can collect on his life insurance. Each of these Deadly Women was sentenced to death.
When Hilma Marie Witte's relationships go bad, she turns to her sons, Eric and John, to help - Eric shoots his father, Paul, and John murders his grandmother, Elaine, with a crossbow so his mother can keep stealing Elaine's money. John exposes his mother as the mastermind of both murders. After drug dealer Greg Smith breaks up with his girlfriend Cindy Baillee, Greg's mother, Lois "Mean Nadean" Smith, a hot-tempered bully who is fiercely protective of her son, responds to rumors that Cindy plans to turn Greg in by luring Cindy away to be sadistically tortured and killed, then has Greg and his new girlfriend, Teresa Baker, clean up the crime scene. Teresa confesses, and Lois is sent to death row. In Glasgow, Scotland, Edith McAlinden is a vagrant, thief, prostitute and alcoholic, and is jailed for assault. On her first night of freedom, a drinking binge turns deadly when Edith stabs her boyfriend, David Gillespie, causing him to bleed to death, and then enlists her 16-year-old son, John, and his friend, Jamie Gray, to murder the two surviving witnesses.
In 1880s Los Angeles, wealthy womanizer Chico Forster courts virtuous teenager Lastania Abarta and convinces her to leave her fiance and elope with him with the promise of marriage, but he forces sex on her and then abandons her. A disgraced Lastania shoots Chico to death for stealing her virtue, and is saved from prison by a novel defense. Diane Borchardt is a well-liked teachers' aide at school, but at home, she is physically and verbally abusive to her husband, Ruben, and his children. When Ruben divorces Diane and leaves her with nothing, she manipulates three students into murdering him, but her students give her up when she is unable to pay them as she promised. Marcela Whaley is controlling and cruel to her girlfriend, Tzatzi Sanchez. When Tzatzi leaves Marcela for Marcela's ex-girlfriend, Marcela hires two thugs to rape and murder Tzatzi, then flees Las Vegas for Mexico, where local authorities prosecute her for the murder as she and Tzatzi are both Mexican nationals.
Gunn-Britt Ashfield loathes her six-year-old son, John, because he reminds her of her ex-husband, Brian. She and her live-in boyfriend, Austin Hughes, falsely accuse John of molesting his sister and brutally beat him to death, then claim John was attacked in a park, but the police are not fooled. Upon her release from prison, Gunn-Britt changes her name to "Angelic." In 1950s Cincinnati, Edythe Klumpp convinces her married lover, Bill Bergen, to pose as her husband so she can get a bank loan, but fears that Bill's wife, Louise, will expose her ruse. Edythe shoots Louise, keeps Louise's corpse in her car while she teaches a sewing class, then tries to burn the body. Drug-addicted stripper Kelly O'Donnell has had a life of tragedy, but she can always count on her old flame, Terry Eleftheriou, to give her money when she needs it. He is repaid with death: Kelly lures him to her apartment with the promise of sex and then bludgeons him repeatedly, and then her lover, Bill Gribble, finishes the job by dismembering Terry's body - while Terry is still alive.
Regina and Margaret DeFrancisco had a bright future, until they embraced the gang lifestyle. After Regina is jailed for dealing drugs, the sisters concoct a ruse to get $1,000 cash from Regina's boyfriend, Oscar Velazquez, but when he too demands repayment, he is repaid with a bullet to the head. The sisters spend two years on the run before they are caught. In Las Vegas in 1863, Laura Fair thinks she's found the perfect man in handsome lawyer Alexander Crittenden, until she learns he's married with kids. Alexander promises to leave his wife and marry Laura, but after seven years of empty promises and lies from Alexander, Laura is tired of being the other woman, and shoots him in front of his wife. Money-hungry Australian Vicki Efandis manipulates her way into the life of wealthy house painter George Marcetta and eventually takes control of all his assets. When he is no longer of use to her, Vicki poisons his dinner with Oxazepam and then burns down his house while he is unconscious.
In Tucson, Arizona, Shawna Forde starts a group of "minutemen" vigilantes to track down illegal Mexican immigrants, and recruits Jason Bush and Albert Gaxiola to join her. In need of fast cash, Forde and her posse murder Raul Flores and his daughter Brisenia and seriously wound his wife Gina, but get away with only a few pieces of jewelry. Shirley Jo Phillips and Wilma Plaster are best friends who enjoy drinking and dancing at country-western bars, but Wilma is nothing more than easy money to Shirley. After stealing a $4,000 check from Wilma, Shirley shoots and then dismembers her to cover up the theft, and is later suspected of killing her own mother in the same way. In late 1980s Chicago, Dorothy Williams is so desperate for cash to support her drug habit that she resorts to preying on the elderly. She strangles one man and stabs another to death, getting away with only $50 each time, and then strangles 97-year-old Mary Harris for her stereo system and $2 cash. She currently serves three life sentences.
Andrea Claire was a 39 year-old former aspiring actress and a call girl. She meets a wealthy older suitor, Robert Sand, in 1981, and the couple marries shortly after meeting. But Claire does not like her fifth husband's penchant for rough sex. One night in 1981, Claire stabs Sand 27 times to death, and in 1982, she attempts to kill her sixth husband. She is serving 26 years to life in prison for her crimes. In 1831 in North Carolina, Frankie Stewart Silver was a teenage bride and a young mother, but she and her husband, Charlie, are an explosive couple. After an angry marital argument, Silver uses a hatchet to hack her husband to death. She dismembers his corpse, then burns and disposes of his remains. After her husband's body is discovered, Silver is hanged in the gallows July 12, 1833. To this day, her father's role in the crime is still contested. In Sydney, Australia, Danielle Stewart is an attractive and flirtatious woman, who captures the attention of 50 year-old bachelor Chaim Kimel. The duo marry, but Stewart has a drinking problem, borderline personality disorder, and tragic past, none of which she can overcome. During an argument with her husband in 2006, Stewart stabs him to death in a drunken rage.